Frontline Plus, K9 Advantix and Advantage… Which Is The Best Flea & Tick Preventative?

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Flea and tick preventatives that I have used
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Wondering about the differences between all of the flea & tick preventatives that are available these days?

I have firsthand experience using 3 of them:

  • Frontline Plus
  • K9 Advantix
  • Advantage

I review each of them below…



(for fleas, ticks)

The Claims:
Offers the long-lasting, most complete flea and tick control available, killing 100% of fleas on your pet within 12 hours and 100% of ticks on your pet within 48 hours.

Best of all, research confirms that Frontline works for an entire month to help keep your pet flea-free.

My Opinion:

I used Frontline Plus on my dogs for years… until my vet made the decision to switch to K9 Advantix.

We never saw a flea or a tick on our dogs the entire time we were using Frontline Plus.

Watch the latest Frontline Plus commercial:

K9 Advantix

(for fleas, ticks, mosquitoes)

The Claims:

For the topical prevention and treatment of fleas, mosquitoes and ticks including deer ticks (the major carrier of Lyme disease), American dog ticks, Brown dog ticks and lone star ticks. K9 Advantix kills and repels fleas, ticks and mosquitoes.

My Opinion:

What makes K9 Advantix so different is it has permethrin in it. Permethrin will kill and repel just about anything. (It’s the same chemical they use to fog dog kennels and horse barns to kill fleas, ticks, flies and practically everything else.) However, we live in an area where ticks are problem, and our dogs have actually had a couple of ticks (either attached or embedded under their skin) while on this product. It does appear that the ticks were shriveled up and dead by the time we spotted them.

Watch the latest K9 Advantix commercial:


(for fleas)

The Claims:

Stops fleas from biting in three to five minutes, and starts killing fleas withing an hour. Within 12 hours of initial application, 98-100% of all existing fleas on pets are dead.

My Opinion:

I used Advantage on my dogs for a short time, but it didn’t make sense not to protect them against ticks and mosquitoes as well, so I switched to K9 Advantix instead. If money is an issue, and/or you’ve only got a really bad flea problem that you’re trying to combat fast, then you might want to try Advantage first.

Watch the latest Advantage commercial:

So Which Is The Best?… My Overall Summary

I think we’re going to go back to Frontline Plus.

While I like that K9 Advantix also repels fleas and (especially) ticks… I don’t think it repels them a full 30 days. Frontline Plus seemed to be more effective on my dogs during the entire 30-day period. And since we use Heartgard (to prevent heartworms from mosquito bites), we don’t actually need the mosquito preventative that Advantix has.

I’ll post an update if we notice any other differences.

Another great product worth considering if you have a flea problem is Frontline Spray. It comes highly recommended by a veterinarian that I listen to on weekend radio. According to veterinarian Carey Carver who appears regularly on Pet Talk with Harrison Forbes, (on on 99.7 WTN), Frontline Spray can be used by itself weekly or even daily, if necessary. Or, you could also use with any of the other preventative measures, including the Advantix collar (which only works for ticks, but it works well). Veterinarians often use it to treat a flea problem on-the-spot in the vet’s office.

More about Frontline Spray.

No Fleas?… Reasons To Still Use A Preventative!

We’ve been very fortunate. We have never had a problem with fleas on any of our dogs.

Each year our vet verifies this for us: STILL NO FLEAS!

Therefore, we use a flea & tick preventative for 2 reasons:

1. Mostly, to prevent fleas from the neighbors’ dogs from jumping onto our dogs; and

2. To keep ticks off the dogs in the summer months (…because we live in an area where ticks are quite prevalent).

Must Read:


I like to help Dog Parents find unique ways to do things that will save time & money -- so I write about "outside the box" Dog Tips and Dog Hacks that most wouldn't think of. I’m a lifelong dog owner -- currently have 2 mixed breed Golden Aussies that we found abandoned on the side of the road as puppies. I've always trained my own dogs and help friends train theirs, as well. Professionally, I worked at a vet and have several friends who are veterinarians -- whom I consult with regularly. (And just because I love animals so much, I also worked at a Zoo for awhile!) I've been sharing my best ideas with others by blogging full-time since 1998 (the same year that Google started... and before the days of Facebook and YouTube). My daily motivation is to help first-time dog owners be better prepared from the first day your new puppy enters your home. I like to help dog owners understand what's 'normal' and what you can expect in terms of living with and training your dog -- how to get through the ups & downs of potty training, chewing, teaching commands, getting your dog to listen, and everything else that takes place during that hectic first year! When I'm not training, walking, grooming, or making homemade treats for my dogs, you will find me at the corner of Good News & Fun Times as publisher of The Fun Times Guide (32 fun & helpful websites). To date, I've written over 600 articles for dog owners on this site! Many of them have upwards of 200K shares.

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